C.V. - Does Size Matter?

In academia, rather than call that piece of paper that lists what we've been up to a "resume," we use the rather pretentious name curriculum vitae, or C.V. for short. And unlike the convention in business that the resume must be kept to one page, no matter what, you can add to your C.V. indefinitely and its size need have no bounds.

Today, mine hit a lucky THIRTEEN pages.

On the one hand, when I apply for a job or a grant, how can they turn down such massive accomplishment? On the other, who the heck would do more than skim such a monstrosity?